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Symbol
Name
ID
Myc
myelocytomatosis oncogene
MGI:97250
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Gastrointestinal hemorrhage
Diffuse alveolar hemorrhage
Bruising susceptibility
Purpura
Ecchymosis
Petechiae
Abnormal lymph node morphology
Lymphadenopathy
Abnormality of the spleen
Disease(s) Associated with MYC
acute promyelocytic leukemia
Burkitt lymphoma

Mouse Phenotypes
cardiovascular system phenotype
abnormal dorsal aorta morphology
abnormal liver sinusoid morphology
liver vascular congestion
abnormal vascular development
abnormal angiogenesis
abnormal vasculogenesis
enlarged heart
distended pericardium
Availability Mouse Genotype
Myctm1Atp/Myctm1Atp *
Myctm1Brd/Myctm1Brd
Myctm1Jlc/Myctm1Jlc
Tg(HBVX*,-Myc)#Skp/Tg(HBVX*,-Myc)#Skp
Tg(HBB-Myc)#Cos/0 *
Myctm2.1Atp/Myctm2.1Atp
Edil3Tg(Sox2-cre)1Amc/Edil3+  (conditional)
*
Myctm2.1Atp/Myctm2.1Atp
Tg(Tek-cre)1Rwng/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory